Holiday Inn Express & Suites St. Louis South - I-55

Welcome to the brand new Holiday Inn Express & Suites St. Louis South - I-55, your modern gateway to St. Louis! Nestled at the convenient intersection of Butler Hill Road and I-55, just a stone's throw south of I-270/255, our hotel puts you within easy reach of all the St. Louis attractions you'll want to explore. Whether you're here for business or a family adventure, you'll appreciate our prime location.

Business travellers will find our hotel a convenient base, with quick access to I-55 connecting you to various parts of the city in minutes. We're situated close to key institutions like the Barnes-Jewish Siteman Cancer Centre and Mercy Health, and just a short drive from major employers such as MetLife, Anheuser-Busch, Cigna, and the National Cemetery Administration.

Leisure guests will love our proximity to iconic St. Louis landmarks. Catch a game at Busch Stadium, marvel at the Gateway Arch, enjoy family fun at Grant's Farm or The Magic House, explore scientific wonders at the St. Louis Science Centre, or visit the renowned St. Louis Zoo and Forest Park. For entertainment, River City Casino is also nearby.

Our non-smoking hotel is designed for your comfort, offering spacious suites, an inviting indoor pool, and a convenient Suite Shop. Start your day right with our complimentary Express Start breakfast, stay connected with complimentary high-speed wired and wireless internet, and unwind in our comfortable Great Room complete with an outdoor patio. Don't forget to enjoy a warm cookie and milk each evening – a little touch of genuine Midwestern hospitality.

Book your stay at the Holiday Inn Express & Suites St. Louis South - I-55 today and experience comfort and convenience that truly shines. We often have rates that beat those found on major booking sites, and we guarantee our best price match. We look forward to welcoming you!