St Louis, United States|Get Location
Hotel Type: 2 Star

Hampton Inn & Suites St. Louis/South I-55

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Front DeskPoolSmart Television

About the hotel

Welcome to Hampton Inn & Suites St. Louis/South I-55, your comfortable base for exploring St. Louis! Situated conveniently near the Barnes Jewish South Campus, our hotel offers easy access to the region's key attractions.

You'll find yourself just a short drive from the scenic Mississippi River, perfect for a leisurely stroll or enjoying the waterfront views. For those looking to explore further afield, the renowned St. Louis Zoo and Washington University in St. Louis are within a 10-minute drive, offering fantastic day-out opportunities for all ages.

At Hampton Inn & Suites St. Louis/South I-55, we pride ourselves on offering a welcoming environment with amenities designed for your comfort. Whether you're here for business or leisure, you can count on a pleasant stay. We often feature rates that are more competitive than those found on major booking sites like Booking.com, Expedia, and LateRooms, and we stand by our Best Price Match guarantee, so you can book with confidence.

Ready to plan your St. Louis adventure? Book your stay at Hampton Inn & Suites St. Louis/South I-55 today and experience genuine hospitality.

Why guests love staying here

Great Location

Conveniently placed near public transport, shopping, and key attractions.

Stylish & Comfortable

Modern rooms with cozy interiors and thoughtful design touches.

Top-notch Amenities

Enjoy breakfast, gym access, and more during your stay.

Excellent Service

Friendly staff and seamless hospitality from check-in to check-out.

Available Rooms

No rooms available for your selected dates

Hampton Inn & Suites St. Louis/South I-55 does not currently have rooms available from 07 Nov 2026 to 10 Nov 2026. Availability may change, so please try alternative dates or explore similar hotels nearby.

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Frequently Asked Questions

Q. What time is check-in at Hampton Inn & Suites St. Louis/South I-55?

A: Check-in at Hampton Inn & Suites St. Louis/South I-55 is from 18:00. Early check-in may be available on request, subject to room availability — contact the hotel directly to arrange it.

Q. What time is check-out at Hampton Inn & Suites St. Louis/South I-55?

A: Check-out at Hampton Inn & Suites St. Louis/South I-55 is by 11:00. Late check-out may be available for an additional fee, subject to availability — please contact the hotel in advance to arrange it.

Q. Where is Hampton Inn & Suites St. Louis/South I-55 located?

A: Hampton Inn & Suites St. Louis/South I-55 is located at 4200 MidAmerica Lane Saint Louis Missouri 63129, St Louis, United States.

Q. Does Hampton Inn & Suites St. Louis/South I-55 offer WiFi?

A: Yes, Hampton Inn & Suites St. Louis/South I-55 offers WiFi for guests for an additional fee. Please contact the hotel for current rates and coverage.

Q. Is parking available at Hampton Inn & Suites St. Louis/South I-55?

A: Yes, Hampton Inn & Suites St. Louis/South I-55 offers parking for guests free of charge. Availability may be limited, so we recommend arriving early or contacting the hotel to reserve a space.

Q. Does Hampton Inn & Suites St. Louis/South I-55 have a swimming pool?

A: Yes, Hampton Inn & Suites St. Louis/South I-55 has a swimming pool for guests to enjoy. Please contact the hotel for pool opening hours and any access guidelines.

Q. Is Hampton Inn & Suites St. Louis/South I-55 pet-friendly?

A: Yes, Hampton Inn & Suites St. Louis/South I-55 is pet-friendly. Please contact the hotel directly to confirm its current pet policy, any applicable fees, and restrictions before your stay.

Q. What is the cancellation policy at Hampton Inn & Suites St. Louis/South I-55?

A: Cancellation policies at Hampton Inn & Suites St. Louis/South I-55 vary by room and rate. Each room option is clearly labelled "Free Cancellation" or "Non Refundable", so you can see the policy before booking. Choose a Free Cancellation rate if you'd like the flexibility to change your plans.

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