Main Street Bed & Breakfast

Welcome to Main Street Bed & Breakfast, a charming escape right in the heart of Hannibal, Missouri. You'll be perfectly situated to explore all the local treasures, with the Bluff City Theater just a stone's throw away and Big River Train Town a mere 3-minute stroll from our doorstep. It’s the ideal base for immersing yourself in the rich history and culture of this iconic riverside town.

History buffs will delight in our proximity to significant landmarks. The renowned Mark Twain Boyhood Home and Museum and Jim's Journey: The Huck Finn Freedom Center are both just 0.2 miles (0.4 km) away, making it incredibly easy to step back in time and follow in the footsteps of literary giants.

While you're here, take advantage of the fantastic opportunities for outdoor adventure. The surrounding area offers wonderful kayaking experiences, allowing you to enjoy the scenic beauty of the Mississippi River. For your convenience, we also provide complimentary valet parking right here at the B&B.

Our cosy establishment offers 3 comfortable guestrooms, each designed to make you feel right at home. We pride ourselves on offering excellent value, often featuring rates lower than those found on major booking sites like Booking.com, Expedia, and LateRooms, all backed by our Best Price Match guarantee. Discover the magic of Hannibal and book your stay at Main Street Bed & Breakfast today!